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Hendrix Students Present Research at Central Arkansas Summer Undergraduate Research Symposium

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Adam De Groodt ’21 answers a question about his poster presentation at the 2019 Central Arkansas Summer Undergraduate Research Symposium. / Photo by Diane Mckinstry, UAMS

CONWAY, Ark. (August 12, 2019) – Twenty Hendrix College students were among more than 115 undergraduates who presented biomedical research at the eighth annual Central Arkansas Summer Undergraduate Research Symposium, held July 24 at the University of Arkansas for Medical Sciences (UAMS) in Little Rock. The symposium was hosted by the UAMS Department of Biochemistry and Molecular Biology, the UAMS Graduate School, the UAMS College of Medicine, and the NIH-supported IDeA Network of Biomedical Research Excellence (INBRE) program.

The symposium consisted of invited oral presentations, posters, and a keynote address. Haven Griffin ’20 was selected to present an oral presentation at the symposium. Of the 10 “Excellence in Research” awards given for top poster presentations, two went to Hendrix students, Adam De Groodt ’21 and J. Tristian Wiles ’21. Dr. Andrea Duina, a professor in the Hendrix Department of Biology, delivered the keynote address, “The Joys and Challenges of Research at an Undergraduate College.”

Hendrix students who presented research at the symposium included:

David Addepalli ’20

Mentor: Dr. Andrea Duina, Hendrix College, Department of Biology

Poster Title: Biochemical characterization of chromatin environments at 3’ ends of genes as a way to uncover mechanisms of FACT complex dissociation from DNA following transcription

Alexis Baker ’20

Mentor: Dr. Richard Murray, Hendrix College, Department of Biology

Poster Title: Identification of genes involved in the development of nociceptive neurons in the mouse dorsal root ganglion

Ashtyn Bell ’22

Mentor: Dr. Julie Gunderson ‘06, Hendrix College, Department of Physics

Poster Title: Unlocking the molecular mechanisms of E. coli MutS

Madison Blue ’20

Mentor: Dr. Robert Eoff, University of Arkansas for Medical Sciences, Department of Biochemistry and Molecular Biology

Poster Title: Investigating DNA Polymerase κ Function as a Barrier to Replication Catastrophe and Genomic Instability in Breast Cancer

Danielle Dilday ’21

Mentor: Dr. Samantha Kendrick, University of Arkansas for Medical Sciences, Department of Biochemistry and Molecular Biology

Poster Title: Using a Proteolysis Targeting Chimera as a Potential Therapeutic Target for Degradation of NEK2 protein in Diffuse Large B-Cell Lymphoma Cell Lines

Adam De Groodt ’21

Mentor: Dr. William Gunderson, Hendrix College, Department of Chemistry

Poster Title: Design of the Fluorino: A Low-cost, Arduino-controlled Fluorometer

Storm Gardner ’20

Mentor: Dr. Andrew Schurko, Hendrix College, Department of Biology

Poster Title: Implementing RNAi and CRISPR/Cas9 to Investigate DNA Repair Genes in Bdelloid Rotifers

Haylee Greer ’20

Mentor: Dr. Alicia Byrd, University of Arkansas for Medical Sciences, Department of Biochemistry and Molecular Biology

Poster Title: Determining Human DNA Helicase B Involvement in Protecting Stalled Replication Forks from Nucleolytic Degradation

Haven Griffin ’20

Mentor: Dr. Giulia Baldini, University of Arkansas for Medical Sciences, Department of Biochemistry and Molecular Biology

Talk Title: Low Fat Diet is Sufficient to Restore Melanocortin-4 Receptor Abundance in Hypothalamic Neurons of Mice Previously Exposed to High Fat Diet and May Protect MC4R-expressing Neurons from Persistent Mitochondrial Damage

Jaycee Hall ’22

Mentor: Dr. Julie Gunderson ‘06, Hendrix College, Department of Physics

Poster Title: Biophysical Characterization of E. coli MutS Using Absorption and Fluorescence Spectroscopies

Ishrar Islam ’22

Mentor: Dr. Giulia Baldini, University of Arkansas for Medical Sciences, Department of Biochemistry and Molecular Biology

Poster Title: The Persistent Effects of Obesity by Exposure to High-Fat Diets on the Livers of Mice Returned to a Healthy Weight

Andrew King ’21

Mentor: Dr. Julie Gunderson ‘06, Hendrix College, Department of Physics

Poster Title: Analysis of MutS-DNA interactions with fluorescence anisotropy

Megan LaPlaunt ’21

Mentor: Dr. Julie Gunderson ‘06, Hendrix College, Department of Physics

Poster Title: Development of a 3D Printable, Arduino-Controlled Scanning Visible Absorption Spectrophotometer

Ivan Midtbust Heger ’21

Mentor: Dr. William Gunderson, Hendrix College, Department of Chemistry

Poster Title: An Open Source Diode Array Visible Absorption Spectrophotometer

Macy Moody ’22

Mentor: Dr. Richard Murray, Hendrix College, Department of Biology

Poster Title: Developmental Expression of the Mouse Cadherin18 Gene

Mattie Nester ’20

Mentor: Dr. Andrea Duina, Hendrix College, Department of Biology

Poster Title: Investigations on possible roles for DNA sequences in promoting dissociation of the FACT complex from the 3’endsof genes following transcription

Sasin Payakachat ’20

Mentor: Dr. Grover Miller, University of Arkansas for Medical Sciences, Department of Biochemistry and Molecular Biology

Poster Title: Identifying How Halogens Impact Bioactivation of Aryl Acetic Acid Nonsteroidal Anti-inflammatory Drugs (NSAIDs)

Thomas Raney ’20

Mentor: Dr. Samantha Kendrick, University of Arkansas for Medical Sciences, Department of Biochemistry and Molecular Biology

Poster Title: Stabilization of DNA G-quadruplexes in CARD11 and MYD88 as a New Therapeutic Approach for ABC Diffuse Large B-cell Lymphoma

Harrison Russell ’20

Mentor: Dr. Julie Gunderson ‘06, Hendrix College, Department of Physics

Poster Title: EPR Spectroscopic Characterization of Divalent Metal Ion COordination in DNA Hairpin Loops

J. Tristian Wiles ’21

Mentor: Dr. Andrew Schurko, Hendrix College, Department of Biology

Poster Title: Investigating DNA Repair in the Bdelloid Rotifer Adineta vaga via Yeast Two-Hybrid Screening and CRISPR-Cas9 Genome Editing

Lillie Wilson ‘22

Mentor: Dr. Richard Murray, Hendrix College, Department of Biology

Poster Title: Development of the mouse vomeronasal organ in the absence of Dlk1-gene function

About Hendrix College

A private liberal arts college in Conway, Arkansas, Hendrix College consistently earns recognition as one of the country’s leading liberal arts institutions, and is featured in Colleges That Change Lives: 40 Schools That Will Change the Way You Think About Colleges. Its academic quality and rigor, innovation, and value have established Hendrix as a fixture in numerous college guides, lists, and rankings. Founded in 1876, Hendrix has been affiliated with the United Methodist Church since 1884. To learn more, visit www.hendrix.edu