Thomas E. Goodwin, Ph.D.

Elbert L. Fausett Distinguished Professor Emeritus of Chemistry

goodwin@hendrix.edu Charles D. Morgan Center for Physical Sciences - Acxiom Hall 213 (501) 450-1252 (501) 450-3829

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Academic Background

Robert A. Welch Foundation Postdoctoral Fellow, Rice University, 1974-75
Ph.D., University of Arkansas, 1974
B.S., Ouachita Baptist University, 1969

Honors, Professional Societies, and Responsibilities

Selected as the recipient of the 2016 American Chemical Society Award for Research at an Undergraduate Institution (Award was presented at the Spring National Meeting of the American Chemical Society in San Diego in March, 2016.)
Co-Editor of the latest volume (13) of Chemical Signals in Vertebrates , B. A. Schulte, M. H. Ferkin and T. E. Goodwin, Eds., Springer Press, NY , 2016.
Keynote speaker at STEM at the Capitol, February 2015 (this was a statewide undergraduate science poster session in the rotunda of the State Capitol in Little Rock).
Co-Organizer (with Bruce Schulte) of the Chemical Signals in Vertebrates at the University of Illinois, July 2014 (meeting jointly with the International Society for Chemical Ecology); Organizer of a symposium entitled Conference "The Role of Bacteria in Vertebrate Chemical Signaling: The Scents of Symbiosis".
Organized and spoke at symposium entitled "Searching for Chemical Signals in Vertebrates: Extractions from Biological Media as a Prelude to GC-MS Analysis"; Chemical Signals in Vertebrates conference, Berlin, Germany, August, 2011.
Attended CUR workshop “Gateways to Best Practices for Undergraduate Program Directors, June, 2011, Washington University.
Council on Undergraduate Research CUR Fellows Award, 2010 for undergraduate research leadership.
Invited speaker at the 23rd William S. Johnson Organic Chemistry Symposium at Stanford University, October 2008
Recipient of the 2007 Pfizer Green Chemistry in Education Award, and presented an award address at Pfizer-St. Louis, October 2008.
One of six keynote speakers at Research Corporation workshop for chemistry and physics faculty, and administrators in Tucson. “Models of Academic Leadership”; August, 2004.
2003 U.S. Professor of the Year (for baccalaureate colleges), awarded by the Carnegie Foundation for the Advancement of Teaching, and the Council for Advancement and Support of Education (CASE)
Recipient of the Faculty Appreciation Award by the Hendrix College Class of 2002 and the Class of 2003 for "excellence in instruction and concern for students’ welfare"
Visiting Fellow, Research School of Chemistry, Australian National University, Canberra (with Professor Martin Banwell), June, 2000
Awarded 1998 David W. Mellor Medal for Chemical Education by the University of New South Wales, Sydney, Australia, and delivered the Mellor Address
1993 Chair, Gordon Research Conference on Heterocyclic Compounds
American Chemical Society
Phi Beta Kappa
Council on Undergraduate Research (CUR) (President, 1992-93)
Co-Editor, CUR Quarterly, 1993-1996
Recipient, Camille and Henry Dreyfus Foundation Scholar/Fellow Program for Undergraduate Institutions (1989)
Board Member, Riddle's Elephant Sanctuary

Recent Grants and Proposals

Tom Goodwin (PI); Co-PIs: Chris Marvin, & Andres Caro: “Acquisition of a 400 MHz NMR Spectrometer to Enhance Faculty and Undergraduate Research at Hendrix College,” NSF-MRI, $258,790, 2010.
Tom Goodwin: National Science Foundation Collaborative Research at Undergraduate Institutions (NSF C-RUI); with Bruce Schulte (Georgia Southern University) and Bets Rasmussen (Oregon Graduate Institute): “Development and Identity of Sexually Dimorphic Signals and Responses by African Elephants,” $842,251, 2002-2006.

Publications

Lydia Greene, Timothy Wallen , Anneke Moresco, Thomas Goodwin, Christina Drea 2016 Reproductive endocrine patterns and volatile urinary compounds of Arctictis binturong : discovering why bearcats smell like popcorn. The Science of Nature 103: 37 [DOI 10.1007/s00114-016-1361-4]
Thomas E. Goodwin, Innocent H. Harelimana , Laura J. MacDonald , Daniel B. Mark , Aline Umuhire Juru , Qin Yin , James A. Engman, Randall A. Kopper, Cheryl F. Lichti, Samuel G. Mackintosh, James D. Shoemaker, Mark V. Sutherland, Alan J. Tackett, Bruce A. Schulte 2016 The Role of Bacteria in Chemical Signals of Elephant Musth: Proximate Causes and Biochemical Pathways. Chapter 6 in Chemical Signals in Vertebrates 13 , B. A. Schulte, M. H. Ferkin and T. E. Goodwin, Eds., Springer Press, NY.
L. E. L. Rasmussen, David R. Greenwood, Thomas E. Goodwin, and Bruce A. Schulte 2016 Asian Elephant Reflections: Chirality Counts. Chapter 17 in Chemical Signals in Vertebrates 13 , B. A. Schulte, M. H. Ferkin and T. E. Goodwin, Eds., Springer Press, NY.
Andres A. Caro, Ava Commissariat, Caroline Dunn, Hyunjoo Kim, Salvador Lorente García, Allen Smith, Harrison Strang, Jake Stuppy , Linda P. Desrochers, Thomas E. Goodwin 2015 Prooxidant and antioxidant properties of salicylaldehyde isonicotinoyl hydrazone iron chelators in HepG2 cells. Biochimica et Biophysica Acta 1850: 2256-2264.
Pugh, C. P., Pouncey, D. L. , Hartman, J. H., Nshimiyimana, R. , Desrochers, L. P., Goodwin, T. E., Boysen, G., & Miller, G. P. 2014 . Multiple UDP-glucuronosyltransferases in human liver microsomes glucuronidate both R - and S -7-hydroxywarfarin into two metabolites. Arch. Biochem. Biophys.564 : 244-253.
Morelli, T. L., Hayes, R. A., Nahrung, H. F., Goodwin, T. E., Harelimana, I. H. , Macdonald, L. J. , & Wright, P. C. 2013 . Relatedness communicated in lemur scent. Naturwissenschaften 100:769-777.
delBarco-Trillo, J., Harelimana, I. H., Goodwin, T. E., & Drea, C. M. 2013 . Chemical differences between voided and bladder urine in the aye-aye ( Daubentonia madagascariensis ): Implications for olfactory communication studies. Am. J. Primatol. 75:695-702.
Drea, C. M., Boulet, M., DelBarco-Trillo, J., Greene, L. K., Sacha, C. R., Goodwin, T. E., & Dubay, G. R. 2013 . The 'secret' in secretions: Methodological considerations in deciphering primate olfactory communication. Am. J. Primatol. 75:621-642.
"Hemiterpenoids and Pyrazines in the Odoriferous Urine of the Maned Wolf ( Chrysocyon brachyurus ," T. E. Goodwin, N. Songsasen, L. J. Broederdorf, B. A. Burkert, C. J. Chen, S.R. Jackson, B. Keplinger, M. E. Rountree, Z. J. Waldrip, M. E. Weddell , L. P. Desrochers, W. K. Baker Jr and J. P. F. G. Helsper, Chapter 13 in Chemical Signals in Vertebrates 13 , 2013 M. I. East and M. Dehnhard, Eds., Springer Press, NY, pp 171-184.
Goodwin, T.E., Broederdorf, L.J., Burkert, B.A., Hirwa, H.H., Mark, D.B., Waldrip, Z.J. , Kopper, R.A., Sutherland, M.V. , Freeman, E.W., Hollister-Smith, J.A., and Schulte, B.A. 2012 . Chemical signals of elephant musth: Temporal aspects of microbially-mediated modifications. J. Chem. Ecol. 38:81-87.
Goodwin, T.E. 2012 . The Art of Organic Synthesis: Green Chemists Find a Better Way, in Chemistry for Changing Times . J. W. Hill, T. W. McCreary, D. K. Kolb. 13 ^th edition. New York: Pearson, p. 254.
delbarco-Trillo, J., Burkert, B. A., Goodwin, B. A., & Drea, C. M. 2011 . Night and day: the comparative study of strepsirrhine primates reveals socioecological and phylogenetic patterns in olfactory signals. J. Evol. Biol. 24:82-98.
Merte, C.E., Goodwin, T.E., & Schulte, B.A. 2010 . Male and female developmental differences in chemosensory investigations by African elephants ( Loxodonta africana ) approaching waterholes. Behav. Ecol. Sociobiol. 64:401-408.
Broederdorf, L.J., Meyer, J.M., Freeman, E.W., Goodwin, T.E., & Schulte, B.A. 2009. The elephants of Addo: An undergraduate research adventure. J. Eleph. Managers Assoc. 20:27-31.
Meyer, J.M., Freeman, E.W., Goodwin, T.E., & Schulte, B.A. 2009. Monitoring African elephant chemical communication and hormone activity in Addo Elephant National Park, South Africa. J. Eleph. Managers Assoc. 20:32-36.
Goodwin, T.E. The Garden of Green Organic Chemistry at Hendrix College. In Changing the Course of Chemistry: Green Chemistry Education; Anastas, P.T., Levy, I.J., Parent, K.E., Eds.; ACS Symposium Series 1011; American Chemical Society: Washington, DC, 2009; pp 37-53.
Goodwin, T.E. & Schulte, B.A. 2009. Prospecting for mammalian chemical signals via solventless extraction techniques: an elephantine task. ChemoSense, 11(2), 9-15.
McKenzie, L.C.; Huffman, L.M.; Hutchison, J.E.; Rogers, C.E.; Goodwin, T.E.; and Spessard, G.O. 2009. Greener Solutions for the Organic Chemistry Teaching Lab: Exploring the Advantages of Alternative Reaction Media. J. Chem. Educ., 86, 488-493.
Loizi, H., Goodwin, T.E., Rasmussen, L.E.L., Whitehouse, A.M. & Schulte, B.A. 2009. Sexual dimorphism in the performance of chemosensory investigatory behaviours by African elephants (Loxodonta africana). Behaviour, 146, 373-392.
"Intrasexual chemical communication and social responses of captive female African elephants, Loxodonta africana" Meyer, J.M.; Goodwin, T.E.; Schulte, B.A. Animal Behavior 2008, 76, 163-174.
Castelda, S.M., Goodwin, T.E. & Schulte, B.A. 2008. Investigating chemical signals in African elephants for convergence with insects and similarities with Asian elephants. Pp. 81-91, in: Proceedings of the 2007 International Elephant Conservation & Research Symposium, Orlando, FL.
"Use of Automated Solid Phase Dynamic Extraction (SPDE)/GC-MS and Novel Macros in the Search for African Elephant Pheromones," T. E. Goodwin, P. A. Brown, M. S. Eggert, M. G. Evola, S. J. House, R. G. Morshedi, M. E. Weddell, C. J. Chen, S. R. Jackson, Y. Aubut, J. Eggert, B. A. Schulte, L. E. L. Rasmussen, Chemical Signals in Vertebrates 11 2007 J. Hurst, R. Beynon, T. Wyatt, & C. Roberts, Eds., Springer Press, NY, pp 25-35.
"Honest Signalling through Chemicals by Elephants with Applications for Care and Conservation", Schulte, B. A.; Freeman, E. W.; Goodwin, T. E.; Hollister-Smith, J.; Rasmussen, L.E.L. Applied Animal Behaviour Science 2007, 102, 344.
"Insect Pheromones and Precursors in Female African Elephant Urine", Goodwin, T. E.; Eggert, M. S.; House, S. J.; Weddell, M. E.; Schulte, B. A.; Rasmussen, L. E. L., Journal of Chemical Ecology 2006, 32, 1849.
"Palladium-catalysed Cross-coupling and Related Reactions Involving Pyrroles" Banwell, M. G.; Goodwin, T. E.; Ng, S.; Smith, J. A.; Wong, D. J. European Journal of Organic Chemistry 2006, 14, 3043.
"Male African elephants ( Loxodonta africana ) can distinguish oestrous status via urinary signals", Bagley, K. R.; Goodwin, T. E.; Rasmussen, L. E. L.; Schulte, B. A. Animal Behaviour 2006 , 71 , 1439.
"African Elephant CHemical COmmunication and Humans in Tanzania", Schulte, B. A.; Napora, E.; Vyas, D.K.; Goodwin, T. E.; Rasmussen, L. E. L. J. Elephant Managers Association 2006 , 17 , 28.
"African elephant births and post-partum events in West Kilimanjaro, Tanzania", Vyas, D. K.; Goodwin, T. E.; Rasmussen, L.E.L.; Schulte, B. A. J. Elephant Managers Association 2006 , 16 , 30.
"Elephant Death Possibly by Constipation", Vyas, D. K.; Goodwin, T. E.; Rasmussen, L.E.L.; Schulte, B. A. Pachyderm 2005 , 39 , 93.
"Chemical Analysis of Preovulatory Female African Elephant Urine: A Search for Putative Pheromones", Goodwin, T. E.; Rasmussen, L. E.L.; Schulte, B. A.; Brown, P. A.; Davis, B. L.; Dill, W. M.; Dowdy, N. C.; Hicks, A. R.; Morshedi, R. G.; Mwanza, D.; Loizi, H., Chemical Signals in Vertebrates 10 2005, R. T. Mason, M. P. LeMaster, and D. Muller-Schwarze, eds., Springer, NY, pp 128-139.
"Hormone Receptor Expression in Interdigital Glands of the Asian Elephant (Elephas maximus)", Lamps, L. W.; Smoller, B. R.; Goodwin, T. E.; Rasmussen, L. E. L., Zoo Biology 2004, 23, 463.
"An Asymptotic Approach to the Development of a Green Organic Chemistry Laboratory", Goodwin, T. E., J. Chem. Educ. 2004, 81, 1187.
"Elephant Chemotactile Communication and Conservation", Schulte, B. A.; Loizi, H.; Bagley, K.; Gray, A.; Stanley, L.; Correll, M.; Goodwin, T. E.; Brown, P. A.; Davis, B. L.; Dill, W. M.; Dowdy, N. C.; Hicks, A. R.; Morshedi, R. G.; Mwanza, D.; Rasmussen, L. E. L. J. Elephant Managers Assoc. 2004, 15, 16-23.
"African Elephant Sesquiterpenes. II. Identification and Synthesis of New Derivatives of 2,3-Dihydrofarnesol", Goodwin, T. E.; Brown, F. D.; Counts, R. W.; Dowdy, N. C.; Fraley, P. L.; Hughes, R. A.; Liu, D. Z.; Mashburn, C. D.; Rankin, J. D.; Roberson, R. S.; Wooley, K. D.; Rasmussen, E. L.; Riddle, S. W.; Riddle, H. S.; Schulz, S. J. Nat. Prod. 2002, 65, 1319.
"Initial Studies on the Source and Cyclic Release Pattern of (Z)-7-Dodecenyl Acetate, the Preovulatory Pheromone of Female Asian Elephants," L. E. L. Rasmussen and T. E. Goodwin, Chem. Senses 2000, 25, 603.
"Characterization of Interdigital Glands in the Asian Elephant (Elephas maximus)", L. W. Lamps, B. R. Smoller, L.E.L. Rasmussen, B. E. Slade, G. Fritsch, and T. E. Goodwin Research in Veterinary Science 2001, 71, 197-200.
"Unwinding of Unnatural Substrates by a DNA Helicase", A. J. Tackett, P. D. Morris, R. Dennis, T. E. Goodwin, K. D. Raney, Biochemistry 2001 , 40 , 543.
"Enhanced Pneumocystis carinii Activity of New Primaquine Analogs", T. E. Goodwin, C. J. Boylan, W. L. Current, J. C. Byrd, C. B. Edwards, D. A. Fuller, J. L. Green, C. D. Larocca, K. D. Raney, A. S. Ross, and W. A. Tucker, Bioorg. Med. Chem. Letters 2000, 10, 2205.
"The First Disclosure and Preliminary Investigation of a Liquid Released from the Ears of African Elephants", H. S. Riddle, S. W. Riddle, L. E. L. Rasmussen, and T. E. Goodwin, Zoo Biology 2000, 19, 475.
"Synthesis of 13C,2H3-Salmeterol: An Analytical Internal Standard for Pharmacokinetic Studies," T. E. Goodwin, X. Zhou, P. A. Haile, P. Breen, P. J. Anderson, F. C. Hiller, and C. M. Compadre Journal of Labelled Compounds and Radiopharmaceuticals, 2000, 43, 65.
"African Elephant Sesquiterpenes," T. E. Goodwin, L. E. L. Rasmussen, A. C. Guinn, S. S. McKelvey, R. Gunawardena, S. W. Riddle, and H. S. Riddle Journal of Natural Products, 1999, 62, 1570.
"A Multistep Synthesis of 4-Nitro-1-Ethynylbenzene Involving Palladium-Catalyzed Carbon-Carbon Bond Formation, Conformational Analysis Using NMR Spectroscopy and Molecular Modeling, Acetal Hydrolysis, and Oxidative Decarbonylation," T. E. Goodwin, E. M. Hurst, and A. S. Ross J. Chem. Educ. 1999 , 76 , 74.
"Observations on the Stereochemistry of Reduction of 2,6-Dimethylcyclohexanones," T. E. Goodwin, J. M. Meacham, M. E. Smith Canadian J. Chem. 1998 , 76 , 1308.
"A Simple Procedure for Solid Phase Synthesis of Peptide Nucleic Acids with N-Terminal Cysteine," T. E. Goodwin, R. D. Holland, J. O. Lay, Jr., and K. D. Raney Bioorg. Med. Chem. Lett. 1998 , 8 , 2231.
"Synthesis of Conformationally Mobile Bicyclic Tetrahydro-1,2-Oxazines by Isomerization of Isoxazolidinylmethyl Tosylates," T. E. Goodwin, D. M. Cousins, S. D. Debenham, J. L. Green, M. L. Guyer, E. G. Jacobs, T. R. Hoye, D. O. Koltun, and J. R. Vyvyan J. Org. Chem. 1998,63, 4485.
"Synthesis of Highly Phenylated Poly(p-phenylene vinylenes) via a Chlorine Precursor Route," B. R. Hsieh, W. C. Wan, Y. Yu, Y. Gao, T. E. Goodwin, S. A. Gonzalez, and W. A. Feld Macromolecules 1998, 31, 631.
"Synthesis of Two New Maytansinoid Model Compounds from Carbohydrate Precursors," T. E. Goodwin, K. R. Cousins, H. M. Crane, P. O. Eason, T. E. Freyaldenhoven, C. C. Harmon, B. K. King, C. D. Larocca, R. L. Lile, S. G. Orlicek, R. W. Pelton, O. L. Shedd, J. S. Swanson, and J. W. Thompson J. Carbohydr. Chem.1998, 17, 323.
"Crystal Structure of (4a,4aa,8aa)-(+)-Octahydro-2-(phenylmethyl)--2 H -1,2-benzoxazin-4-ol, 4-Methylbenzenesulfonate (ester)," W. Cordes, J. L. Smith, M. C. Noble, T. E. Goodwin, D. M. Cousins, and E. G. Jacobs J. Chem. Cryst. 1998 , 28 , 133.
"How to Get Started in Research," a booklet published by the Council on Undergraduate Research, 1995 (Co-authored and edited with B. Holmes, UNC-Asheville) [2nd Edition, 1999].
"Notes from a Fledgling Elephant Researcher," T. E. Goodwin Journal of the Elephant Manager’s Association 1997, 8, 42.
Synthesis of Highly Phenylated Poly(p-phenylenevinylenes) via Halogen Precursor Route (HPR)," S. A. Gonzalez, T. E. Goodwin, W. A. Feld, and B. R. Hsieh Polymer Preprints 1997, 38, April Issue.
"Stereoselectivity Reversals in Conjugate Additions to a 2,3-Dihydro-4H-pyran-4-one," T. E. Goodwin, N. M. Rothman, K. L. Salazar, S. L. Sorrels, and F. E. Evans J. Org. Chem.1992, 57, 2469.
"Preparation of an Aromatic Synthon for Maytansinoid Synthesis," T. E. Goodwin, S. G. Orlicek, N. R. Adams, L. A. Covey-Morrison, J. S. Jenkins, and G. L. Templeton J. Org. Chem.1985, 50, 5889.
"Stereoselective addition of organocopper reagents to a novel carbohydrate-derived 2,3-dihydro-4H-pyran-4-one," T. E. Goodwin, C. M. Crowder, R. B.White, J. S. Swanson, F. E. Evans, and W. L. Meyer J. Org. Chem.1983, 48, 376.
"Synthesis of (E)-1-aryl-2-methyl-3-alkyl-2-propen-1-ones via sulfoxide sulfenate ester rearrangements," T. E. Goodwin, D. G. Ratcliff, C. M. Crowder, and N. K. Seitzinger J. Org. Chem.1982, 47, 815.